WASHINGTON, D.C. — October 29, 2025 — NVIDIA today announced a groundbreaking initiative in collaboration with the U.S. Department of Energy’s national laboratories and some of the nation’s most prominent technology leaders to construct America’s next-generation AI infrastructure. This ambitious effort aims to accelerate scientific discovery, strengthen national security, drive economic growth, and lay the groundwork for the next industrial revolution, one driven by artificial intelligence.
“We are at the dawn of the AI industrial revolution that will define the future of every industry and nation,” said Jensen Huang, founder and CEO of NVIDIA. “It is imperative that America lead the race to the future — this is our generation’s Apollo moment. Together with our partners, we are building the most advanced AI infrastructure ever created, ensuring that the world’s AI runs on American innovation, openness, and collaboration for the benefit of all.”
Accelerating AI Research Across U.S. National Laboratories
NVIDIA is collaborating with the U.S. Department of Energy (DOE) to provide advanced AI infrastructure at Argonne National Laboratory and Los Alamos National Laboratory (LANL). Seven new AI systems are set to be released, aiming to accelerate breakthroughs in security, science, and energy applications.
At Argonne, NVIDIA and Oracle are building Solstice, the DOE’s largest AI supercomputer, featuring a record-breaking 100,000 NVIDIA Blackwell GPUs. A second system, Equinox, equipped with 10,000 GPUs, will launch in 2026. Together, these systems will deliver an unprecedented 2,200 exaflops of AI performance, empowering researchers to solve complex scientific challenges faster than ever before.
Argonne will also debut three additional NVIDIA-based systems — Tara, Minerva, and Janus — designed to democratize AI access for scientists nationwide.
“Argonne’s collaboration with NVIDIA and Oracle represents a pivotal step in advancing the nation’s AI and computing infrastructure,” said Paul K. Kearns, director of Argonne National Laboratory. “Together, we’re shaping the foundation for the next generation of computing that will power discovery for decades to come.”
At Los Alamos, NVIDIA technology will power two next-generation systems — Mission and Vision — built by HPE and connected through NVIDIA’s Quantum-X800 InfiniBand network fabric. These systems, enabled by the Vera Rubin platform, will accelerate advanced research in climate modeling, materials science, and quantum computing.
“Harnessing this level of computational performance is essential to tackling complex scientific and national security challenges,” said Thom Mason, director of Los Alamos National Laboratory. “Our partnership with NVIDIA keeps us at the forefront of innovation.”
NVIDIA AI Factory Research Center: The Future of Intelligent Infrastructure
NVIDIA also revealed plans for a new AI Factory Research Center at Digital Realty in Virginia, powered by the Vera Rubin platform. This facility will drive breakthroughs in generative AI, scientific computing, and advanced manufacturing. It also lays the foundation for NVIDIA Omniverse DSX, a blueprint for gigawatt-scale AI factories designed to seamlessly integrate physical and digital systems through digital twins and autonomous control.
The Omniverse DSX blueprint will enable self-optimizing AI factories that enhance energy efficiency, scalability, and sustainability across industrial sectors.
Collaborating with a wide network of partners, NVIDIA is building this ecosystem from the ground up:
- Engineering leaders Bechtel and Jacobs are embedding digital twins into validated architectural and energy system designs.
- Energy and cooling pioneers, including Eaton, GE Vernova, Hitachi, Mitsubishi Electric, Schneider Electric, Siemens, Tesla, Trane Technologies, and Vertiv, are developing power-conversion and cooling systems optimized for NVIDIA platforms.
- AI and software innovators such as Cadence, Phaidra, PTC, Emerald AI, and Siemens are building intelligent agents to autonomously manage AI factory lifecycles and improve grid flexibility and resilience.
U.S. Companies Invest in AI Factories to Power National Growth
America’s leading technology providers are investing heavily in NVIDIA-powered AI systems to accelerate innovation across industries and the public sector.
System makers such as Cisco, Dell Technologies, HPE, and Supermicro are integrating NVIDIA GPUs and software into secure, scalable infrastructure solutions. Cisco, for example, is launching the Nexus N9100 switch series featuring NVIDIA Spectrum-X Ethernet silicon, designed for high-speed AI workloads.
Cloud providers are also expanding rapidly:
- Akamai is rolling out its Inference Cloud across 20 global sites using NVIDIA RTX PRO™ Servers.
- CoreWeave Federal will deliver secure AI cloud infrastructure for the U.S. government, running on NVIDIA GPUs.
- Google Cloud, Oracle, and Microsoft Azure are scaling up NVIDIA Blackwell GPU systems to accelerate enterprise and research AI workloads nationwide.
- xAI is constructing its Colossus 2 data center in Memphis, Tennessee, to house over 500,000 NVIDIA GPUs, supporting the frontier of next-generation AI model development.
AI Infrastructure Driving Industry Transformation
Beyond government and cloud sectors, U.S. enterprises are building AI factories to revolutionize healthcare and life sciences.
Eli Lilly is creating the pharmaceutical industry’s most powerful AI factory using NVIDIA DGX SuperPOD™ systems, accelerating biomedical research and drug discovery.
Mayo Clinic is leveraging NVIDIA DGX B200 systems to power AI-driven medical research and personalized care, supported by one of the world’s largest databases of patient records and pathology slides.
These efforts mark a turning point in America’s technological leadership — combining public and private innovation to usher in a new era of AI-driven productivity, security, and discovery.
About NVIDIA
NVIDIA (NASDAQ: NVDA) is the global leader in AI and accelerated computing. Its innovations in graphics, high-performance computing, and artificial intelligence are transforming industries, from gaming to healthcare to autonomous vehicles.
For more information about NVIDIA’s collaborations and AI infrastructure initiatives, visit www.nvidia.com.
Media Contact:
Kristin Uchiyama
Enterprise and Edge Computing
+1-408-486-2248
kuchiyama@nvidia.com
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